Closed-loop insulin delivery improves glycaemic control during mixed elective surgery

Fully closed-loop subcutaneous insulin delivery improves glycemic control in people undergoing elective surgery.

A new study has found that fully closed-loop subcutaneous insulin delivery is more beneficial than standard insulin therapy for individuals having elective surgery.

During a randomised controlled trial, the team of researchers examined 45 adults whilst they underwent different surgeries, such as orthopaedic, neuro, thoracic, abdominal and vascular surgery.

As part of the study, 50% of the participants received fully closed-loop insulin delivery with fast-acting insulin aspart and the other half received standard insulin therapy.

The results stated: “The mean proportion of time that sensor glucose was in the target range was 76.7 ± 10.1% in the closed-loop group and 54.7 ± 20.8% in the control group (mean difference 22.0 percentage points [95% CI 11.9; 32.0%]; P < 0.001).

“No episodes of severe hypoglycaemia (<3.0 mmol/L) or hyperglycaemia with ketonemia or any study-related adverse events occurred in either group, reported David Herzig, of Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, University Hospital of Bern, Switzerland, and colleagues.”

Read the study here.

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